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產品英文名稱：TGF-β1,human，TGF-β1-100
產品中文名稱：人TGF-β1蛋白
TGF-β1產品介紹：
轉化生長因子β(transforming growth factor)家族由一類結構、功能相關的多肽生長因子 亞家族組成，其中包括TGF-β、活化素(activin)、骨形態發生蛋白(BMP)、生長分化因子( GDF)等。TGF-β除了影響細胞的增殖、分化，還在胚胎發育、胞外基質形成、 骨的形成和重建等方面起著重要作用。TGF-β家族成員廣泛存在于從果蠅到人多種生物的 各種組織中，對正常細胞、癌變細胞都有著顯著作用。
TGF-β1產品特性：
? TGF-β1活性經過人源細胞鑒定，純度高。
? 生物活性在人源293細胞經過SMAD實驗鑒定The EC50為 0.1–1.0 ng/ml。
? TGF-β1產品經過SDS-PAGE 和HPLC雙層鑒定純度大于95%。
TGF-β1產品英文簡述：
Members of TGF-family are multifunctional cytokines that regulate cell proliferation, growth, differentiation and migration as well as synthesis of the extracellular matrix. The three human isoforms, TGF- 1, 2, 3, signal through the same receptor and elicit similar biological responses. The release of biologically active TGF-isoform from a latent complex involves proteolytic processing of the complex. TGF-1 is the most abundant isoform secreted by almost all cell types. Human TGF-1 is a 25.0kDa protein with each subunit containing 112 amino acid residues, linked by a disulfide bond.
? Purity: Greater than 95% as determined by SDS-PAGE and HPLC analyses
? Biological Activity: The activity was determined by using a SMAD reporter gene assay in human 293 cells. The EC50 ranges from 0.1 – 1.0 ng/ml.
? For Research Use Only. Not for Use in Humans.
重慶市華雅干細胞技術有限公司